Exacerbated Age-Related Hippocampal Alterations of Microglia Morphology, β-Amyloid and Lipofuscin Deposition and Presenilin Overexpression in <i>Per1</i>^−/−-Mice

• 主要な著者: Jan Hendrik Börner (著者), Oliver Rawashdeh (著者), Abdelhaq Rami (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

In humans, alterations of circadian rhythms and autophagy are linked to metabolic, cardiovascular and neurological dysfunction. Autophagy constitutes a specific form of cell recycling in many eukaryotic cells. Aging is the principal risk factor for the development of neurodegenerative diseases. Thus...