Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy.

Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy.

BACKGROUND:Pathophysiological mechanisms are still incompletely understood for leprosy, an urgent public health issue in Brazil. Complement receptor 1 (CR1) binds complement fragments C3b/C4b deposited on mycobacteria, mediating its entrance in macrophages. We investigated CR1 polymorphisms, gene ex...

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Main Authors: Gabriela Canalli Kretzschmar (Author), Luana Caroline Oliveira (Author), Renato Mitsunori Nisihara (Author), Thirumalaisamy P Velavan (Author), Sérvio Túlio Stinghen (Author), Ewalda R S Stahlke (Author), Maria Luiza Petzl-Erler (Author), Iara José T de Messias-Reason (Author), Angelica Beate Winter Boldt (Author)
Format: Book
Published: Public Library of Science (PLoS), 2018-08-01T00:00:00Z.
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3rd Floor Main Library

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