In Vitro Activities of Ceftazidime-Avibactam and Aztreonam-Avibactam at Different Inoculum Sizes of Extended-Spectrum β-Lactam-Resistant Enterobacterales Blood Isolates

• Main Authors: Moonsuk Bae (Author), Taeeun Kim (Author), Joung Ha Park (Author), Seongman Bae (Author), Heungsup Sung (Author), Mi-Na Kim (Author), Jiwon Jung (Author), Min Jae Kim (Author), Sung-Han Kim (Author), Sang-Oh Lee (Author), Sang-Ho Choi (Author), Yang Soo Kim (Author), Yong Pil Chong (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

β-lactam-avibactam combinations have been proposed as carbapenem-sparing therapies, but little data exist on their in vitro activities in infections with high bacterial inocula. We investigated the in vitro efficacies and the inoculum effects of ceftazidime-avibactam and aztreonam-avibactam against...