In vivo testing of mucus-permeating nanoparticles for oral insulin delivery using Caenorhabditis elegans as a model under hyperglycemic conditions

The aim was to evaluate the potential of mucus-permeating nanoparticles for the oral administration of insulin. These nanocarriers, based on the coating of zein nanoparticles with a polymer conjugate containing PEG, displayed a size of 260 nm with a negative surface charge and an insulin payload of...

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Main Authors: Ana L. Martínez-López (Author), Carlos J. González-Navarro (Author), Paula Aranaz (Author), José L. Vizmanos (Author), Juan M. Irache (Author)
Format: Book
Published: Elsevier, 2021-04-01T00:00:00Z.
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