Involvement of Tryptase and Proteinase-Activated Receptor-2 in Spontaneous Itch-Associated Response in Mice With Atopy-like Dermatitis

• Main Authors: Kenichiro Tsujii (Author), Tsugunobu Andoh (Author), Haruna Ui (Author), Jung-Bum Lee (Author), Yasushi Kuraishi (Author)
• Formato: Livro
• Publicado em: Elsevier, 2009-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

This study investigated the involvement of tryptase and proteinase-activated receptor (PAR) subtypes in spontaneous scratching, an itch-associated behavior, in NC mice. This strain of mice showed chronic atopy-like dermatitis and severe spontaneous scratching, when kept a long time in a conventional...