Biologically Potent Benzimidazole-Based-Substituted Benzaldehyde Derivatives as Potent Inhibitors for Alzheimer's Disease along with Molecular Docking Study

• Main Authors: Bushra Adalat (Author), Fazal Rahim (Author), Wajid Rehman (Author), Zarshad Ali (Author), Liaqat Rasheed (Author), Yousaf Khan (Author), Thoraya A. Farghaly (Author), Sulaiman Shams (Author), Muhammad Taha (Author), Abdul Wadood (Author), Syed A. A. Shah (Author), Magda H. Abdellatif (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Twenty-one analogs were synthesized based on benzimidazole, incorporating a substituted benzaldehyde moiety (<b>1</b>-<b>21</b>). These were then screened for their acetylcholinesterase and butyrylcholinesterase inhibition profiles. All the derivatives except <b>13</...