Impact of Linker Modification and PEGylation of Vancomycin Conjugates on Structure-Activity Relationships and Pharmacokinetics

• Main Authors: Florian Umstätter (Author), Julia Werner (Author), Leah Zerlin (Author), Eric Mühlberg (Author), Christian Kleist (Author), Karel D. Klika (Author), Tobias Hertlein (Author), Barbro Beijer (Author), Cornelius Domhan (Author), Stefan Zimmermann (Author), Knut Ohlsen (Author), Uwe Haberkorn (Author), Walter Mier (Author), Philipp Uhl (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As multidrug-resistant bacteria represent a concerning burden, experts insist on the need for a dramatic rethinking on antibiotic use and development in order to avoid a post-antibiotic era. New and rapidly developable strategies for antimicrobial substances, in particular substances highly potent a...