Cleavage Stimulation Factor Subunit 2: Function Across Cancers and Potential Target for Chemotherapeutic Drugs

• Main Authors: Linfei Feng (Author), Fengyang Jing (Author), Xiaofeng Qin (Author), Liming Zhou (Author), Yujie Ning (Author), Jun Hou (Author), Weihao Kong (Author), Youming Zhu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The cleavage stimulation factor subunit complex is involved in the cleavage and polyadenylation of 3'-end pre-mRNAs that regulate mRNA formation and processing. However, cleavage stimulation factor subunit 2 (CSTF2) was found to play a more critical regulatory role across cancers. General cance...