In Vitro Evaluation of Self-Nano-Emulsifying Drug Delivery Systems (SNEDDS) Containing Room Temperature Ionic Liquids (RTILs) for the Oral Delivery of Amphotericin B

• Main Authors: Eleni Kontogiannidou (Author), Thomas Meikopoulos (Author), Helen Gika (Author), Emmanuel Panteris (Author), Ioannis S. Vizirianakis (Author), Anette Müllertz (Author), Dimitrios G. Fatouros (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amphotericin B (AmpB), one of the most commonly used agents in the treatment of severe fungal infections and life-threatening parasitic diseases such as visceral Leishmaniasis, has a negligible oral bioavailability, primarily due to a low solubility and permeability. To develop an oral formulation,...