Dysregulated Immunometabolism Is Associated with the Generation of Myeloid-Derived Suppressor Cells in Staphylococcus aureus Chronic Infection

• Main Authors: Oliver Dietrich (Author), Alexander Heinz (Author), Oliver Goldmann (Author), Robert Geffers (Author), Andreas Beineke (Author), Karsten Hiller (Author), Antoine-Emmanuel Saliba (Author), Eva Medina (Author)
• Format: Book
• Published: Karger Publishers, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myeloid-derived suppressor cells (MDSCs) are a compendium of immature myeloid cells that exhibit potent T-cell suppressive capacity and expand during pathological conditions such as cancer and chronic infections. Although well-characterized in cancer, the physiology of MDSCs in the infection setting...