Docetaxel-Loaded Methoxy poly(ethylene glycol)-poly (L-lactic Acid) Nanoparticles for Breast Cancer: Synthesis, Characterization, Method Validation, and Cytotoxicity

• Main Authors: Shumaila Miraj (Author), Hamid Saeed (Author), Mehwish Iqtedar (Author), Norah A. Albekairi (Author), Nadeem Ahmed (Author), Muhammad Zeeshan Danish (Author), Muhammad Islam (Author), Muhammad Fawad Rasool (Author), Kashif Mairaj Deen (Author), Hassaan Anwer Rathore (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to synthesize and characterize DTX-mPEG-PLA-NPs along with the development and validation of a simple, accurate, and reproducible method for the determination and quantification of DTX in mPEG-PLA-NPs. The prepared NPs were characterized using AFM, DLS, zetasizer, and drug release k...