Radiolabeling and quality control of therapeutic radiopharmaceuticals: optimization, clinical implementation and comparison of radio-TLC/HPLC analysis, demonstrated by [177Lu]Lu-PSMA

• Main Authors: Eline L. Hooijman (Author), Carolline M. Ntihabose (Author), Thom G. A. Reuvers (Author), Julie Nonnekens (Author), Else A. Aalbersberg (Author), Jordy R. J. P. van de Merbel (Author), Judith E. Huijmans (Author), Stijn L. W. Koolen (Author), Jeroen J. M. A. Hendrikx (Author), Erik de Blois (Author)
• Format: Book
• Published: SpringerOpen, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Radiopharmaceuticals are considered as regular medicinal products and therefore the same regulations as for non-radioactive medicinal products apply. However, specific aspects should be considered due to the radiochemical properties. Radiopharmaceutical dedicated monographs are d...