Synthesis and Preliminary Characterization of Putative Anle138b-Centered PROTACs against α-Synuclein Aggregation

• Main Authors: Martina Pedrini (Author), Angelo Iannielli (Author), Lorenzo Meneghelli (Author), Daniele Passarella (Author), Vania Broccoli (Author), Pierfausto Seneci (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The search for disease-modifying agents targeted against Parkinson's disease led us to rationally design a small array of six Anle138b-centered PROTACs, <b>7a</b>,<b>b</b>, <b>8a</b>,<b>b</b> and <b>9a</b>,<b>b</b>, targeti...