The Balancing of Peroxynitrite Detoxification between Ferric Heme-Proteins and CO₂: The Case of Zebrafish Nitrobindin

• Main Authors: Giovanna De Simone (Author), Andrea Coletta (Author), Alessandra di Masi (Author), Massimo Coletta (Author), Paolo Ascenzi (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nitrobindins (Nbs) are all-β-barrel heme proteins and are present in prokaryotes and eukaryotes. Although their function(s) is still obscure, Nbs trap NO and inactivate peroxynitrite. Here, the kinetics of peroxynitrite scavenging by ferric <i>Danio rerio</i> Nb (<i>Dr</i>-Nb...