Blood exosome sensing via neuronal insulin-like growth factor-1 regulates autism-related phenotypes

• Main Authors: Lei Chen (Author), Xi-Yue Xiong (Author), Tong-Tong Yao (Author), Lue-Ning Gui (Author), Fan Luo (Author), Yang Du (Author), Yong Cheng (Author)
• Format: Bog
• Udgivet: Elsevier, 2023-11-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

The development and progression of autism spectrum disorder (ASD) is characterized by multiple complex molecular events, highlighting the importance of the prefrontal brain regions in this process. Exosomes are nanovesicles that play a critical role in intercellular communication. Peripheral systems...