Validation of miR-20a as a Tumor Suppressor Gene in Liver Carcinoma Using Hepatocyte-Specific Hyperactive piggyBac Transposons

Validation of miR-20a as a Tumor Suppressor Gene in Liver Carcinoma Using Hepatocyte-Specific Hyperactive piggyBac Transposons

We established a semi-high-throughput in vivo screening platform using hyperactive piggyBac (hyPB) transposons (designated as PB-miR) to identify microRNAs (miRs) that inhibit hepatocellular carcinoma (HCC) development in vivo, following miR overexpression in hepatocytes. PB-miRs encoding six differ...

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Main Authors: Jaitip Tipanee (Author), Mario Di Matteo (Author), Warut Tulalamba (Author), Ermira Samara-Kuko (Author), Jiri Keirsse (Author), Jo A. Van Ginderachter (Author), Marinee Khim Chuah (Author), Thierry VandenDriessche (Author)
Format: Book
Published: Elsevier, 2020-03-01T00:00:00Z.
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