The essential roles of FXR in diet and age influenced metabolic changes and liver disease development: a multi-omics study

The essential roles of FXR in diet and age influenced metabolic changes and liver disease development: a multi-omics study

Abstract Background Aging and diet are risks for metabolic diseases. Bile acid receptor farnesoid X receptor (FXR) knockout (KO) mice develop metabolic liver diseases that progress into cancer as they age, which is accelerated by Western diet (WD) intake. The current study uncovers the molecular sig...

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Main Authors: Guiyan Yang (Author), Prasant K. Jena (Author), Ying Hu (Author), Lili Sheng (Author), Shin-Yu Chen (Author), Carolyn M. Slupsky (Author), Ryan Davis (Author), Clifford G. Tepper (Author), Yu-Jui Yvonne Wan (Author)
Format: Book
Published: BMC, 2023-02-01T00:00:00Z.
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