Pauci- and Multibacillary Leprosy: Two Distinct, Genetically Neglected Diseases.

• Main Authors: Jean Gaschignard (Author), Audrey Virginia Grant (Author), Nguyen Van Thuc (Author), Marianna Orlova (Author), Aurélie Cobat (Author), Nguyen Thu Huong (Author), Nguyen Ngoc Ba (Author), Vu Hong Thai (Author), Laurent Abel (Author), Erwin Schurr (Author), Alexandre Alcaïs (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

After sustained exposure to Mycobacterium leprae, only a subset of exposed individuals develops clinical leprosy. Moreover, leprosy patients show a wide spectrum of clinical manifestations that extend from the paucibacillary (PB) to the multibacillary (MB) form of the disease. This "polarizatio...