Metformin Shortens Prolonged QT Interval in Diabetic Mice by Inhibiting L-Type Calcium Current: A Possible Therapeutic Approach

• 主要な著者: Hui Wang (著者), Cao Wang (著者), Yuan Lu (著者), Yan Yan (著者), Dongjing Leng (著者), Shanshan Tian (著者), Dongjie Zheng (著者), Zhiguo Wang (著者), Yunlong Bai (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The incidence and mortality of cardiovascular disease in diabetic patients are 2-3 times higher than those in non-diabetic patients. Abnormal function of the L-type calcium channel in myocardial tissue might result in multiple cardiac disorders such as a prolonged QT interval. Therefore, QT prolonga...