Pharmacokinetics and clinical response to single agent rucaparib in a dialysis dependent patient with BRCA associated breast and recurrent ovarian cancer

A 56-year old woman with BRCA-associated breast cancer and recurrent ovarian cancer was treated with a poly (ADP-ribose) polymerase enzyme (PARP) inhibitor, rucaparib, in the setting of dialysis-dependence which required dose modification. Rucaparib trough levels were obtained before and after dialy...

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Main Authors: Justin A. Harold (Author), Stephanie C. Free (Author), William H. Bradley (Author)
Format: Book
Published: Elsevier, 2018-11-01T00:00:00Z.
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3rd Floor Main Library

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