Critical role of tumor necrosis factor-α in the early process of wound healing in skin

• Main Authors: Masae Ritsu (Author), Kazuyoshi Kawakami (Author), Emi Kanno (Author), Hiromasa Tanno (Author), Keiko Ishii (Author), Yoshimichi Imai (Author), Ryoko Maruyama (Author), Masahiro Tachi (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor necrosis factor (TNF)-α is quickly released and initiates inflammation at wound tissues, but its precise role in wound healing is not fully understood. We examined the contribution of this cytokine to the early process of healing using a mouse model with full-thickness wounds in skin. TNF-α sy...