Long-Lasting, Antinociceptive Effects of pH-Sensitive Niosomes Loaded with Ibuprofen in Acute and Chronic Models of Pain

• Main Authors: Francesca Marzoli (Author), Carlotta Marianecci (Author), Federica Rinaldi (Author), Daniele Passeri (Author), Marco Rossi (Author), Paola Minosi (Author), Maria Carafa (Author), Stefano Pieretti (Author)
• Format: Book
• Published: MDPI AG, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ibuprofen is one of the non-steroidal anti-inflammatory drugs (NSAIDs) widely used to treat pain conditions. NSAIDs encounter several obstacles to passing across biological membranes. To overcome these constraints, we decided to study the effects of a new pH-sensitive formulation of niosomes contain...