Determining mutational burden and signature using RNA-seq from tumor-only samples
Abstract Background Traditionally, mutational burden and mutational signatures have been assessed by tumor-normal pair DNA sequencing. The requirement of having both normal and tumor samples is not always feasible from a clinical perspective, and led us to investigate the efficacy of using RNA seque...
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| Main Authors: | , , , , |
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| Format: | Book |
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BMC,
2021-03-01T00:00:00Z.
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A1234.567 |
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