Infection with chikungunya virus confers heterotypic cross-neutralizing antibodies and memory B-cells against other arthritogenic alphaviruses predominantly through the B domain of the E2 glycoprotein.

Infections with Chikungunya virus, a mosquito-borne alphavirus, cause an acute febrile syndrome often followed by chronic arthritis that persists for months to years post-infection. Neutralizing antibodies are the primary immune correlate of protection elicited by infection, and the major goal of va...

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Príomhchruthaitheoirí: John M Powers (Údar), Zoe L Lyski (Údar), Whitney C Weber (Údar), Michael Denton (Údar), Magdalene M Streblow (Údar), Adam T Mayo (Údar), Nicole N Haese (Údar), Chad D Nix (Údar), Rachel Rodríguez-Santiago (Údar), Luisa I Alvarado (Údar), Vanessa Rivera-Amill (Údar), William B Messer (Údar), Daniel N Streblow (Údar)
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Foilsithe / Cruthaithe: Public Library of Science (PLoS), 2023-03-01T00:00:00Z.
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