Adipocyte-Based Cell Therapy in Oncology: The Role of Cancer-Associated Adipocytes and Their Reinterpretation as Delivery Platforms

• Main Authors: Raluca Munteanu (Author), Anca Onaciu (Author), Cristian Moldovan (Author), Alina-Andreea Zimta (Author), Diana Gulei (Author), Angelo V. Paradiso (Author), Vladimir Lazar (Author), Ioana Berindan-Neagoe (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer-associated adipocytes have functional roles in tumor development through secreted adipocyte-derived factors and exosomes and also through metabolic symbiosis, where the malignant cells take up the lactate, fatty acids and glutamine produced by the neighboring adipocytes. Recent research has d...