Condition-specific gene co-expression network mining identifies key pathways and regulators in the brain tissue of Alzheimer's disease patients

• Main Authors: Shunian Xiang (Author), Zhi Huang (Author), Tianfu Wang (Author), Zhi Han (Author), Christina Y. Yu (Author), Dong Ni (Author), Kun Huang (Author), Jie Zhang (Author)
• Format: Book
• Published: BMC, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Gene co-expression network (GCN) mining is a systematic approach to efficiently identify novel disease pathways, predict novel gene functions and search for potential disease biomarkers. However, few studies have systematically identified GCNs in multiple brain transcriptomic dat...