Exploring the potential of flubendazole in filariasis control: evaluation of the systemic exposure for different pharmaceutical preparations.

• Váldodahkkit: Laura Ceballos (Dahkki), Charles Mackenzie (Dahkki), Timothy Geary (Dahkki), Luis Alvarez (Dahkki), Carlos Lanusse (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The goal of elimination of the human filariases would benefit greatly from the use of a macrofilaricidal agent. In vivo trials in humans and many experimental animal models suggest that flubendazole (FLBZ) is a highly efficacious macrofilaricide. However, since serious injection site reactions were...