Innovative Drugs to Target Renal Inflammation in Sepsis: Alkaline Phosphatase

• Main Authors: Femke Hümmeke-Oppers (Author), Pleun Hemelaar (Author), Peter Pickkers (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Fag: article
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Sepsis-related mortality roughly doubles when acute kidney injury (AKI) occurs and end-stage renal disease is more common in sepsis-associated AKI survivors. So far, no licensed treatment for the prevention of AKI is available, however the data on alkaline phosphatase (AP) is promising and might cha...