Nanoparticulate Drug Delivery Strategies to Address Intestinal Cytochrome P450 CYP3A4 Metabolism towards Personalized Medicine

• मुख्य लेखकों: Rui Xue Zhang (लेखक), Ken Dong (लेखक), Zhigao Wang (लेखक), Ruimin Miao (लेखक), Weijia Lu (लेखक), Xiao Yu Wu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Drug dosing in clinical practice, which determines optimal efficacy, toxicity or ineffectiveness, is critical to patients' outcomes. However, many orally administered therapeutic drugs are susceptible to biotransformation by a group of important oxidative enzymes, known as cytochrome P450s (CYP...