The Role of LNK (SH2B3) in the Regulation of JAK-STAT Signalling in Haematopoiesis

• Main Authors: Rhiannon Morris (Author), Liesl Butler (Author), Andrew Perkins (Author), Nadia J. Kershaw (Author), Jeffrey J. Babon (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

LNK is a member of the SH2B family of adaptor proteins and is a non-redundant regulator of cytokine signalling. Cytokines are secreted intercellular messengers that bind to specific receptors on the surface of target cells to activate the Janus Kinase-Signal Transducer and Activator of Transcription...