A Novel Semi-Solid Self-Emulsifying Formulation of Aprepitant for Oral Delivery: An In Vitro Evaluation

• Hauptverfasser: Hakan Nazlı (Verfasst von), Burcu Mesut (Verfasst von), Özlem Akbal-Dağıstan (Verfasst von), Yıldız Özsoy (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2023-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Aprepitant is the first member of a relatively new antiemetic drug class called NK₁ receptor antagonists. It is commonly prescribed to prevent chemotherapy-induced nausea and vomiting. Although it is included in many treatment guidelines, its poor solubility causes bioavailabi...