In Vitro Anti-cancer Activity of Adipose-Derived Mesenchymal Stem Cells Increased after Infection with Oncolytic Reovirus

• Main Authors: Abouzar Babaei (Author), Hossein Bannazadeh Baghi (Author), Akram Nezhadi (Author), Zahra Jamalpoor (Author)
• Formato: Libro
• Publicado: Tabriz University of Medical Sciences, 2021-02-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Purpose: Reovirus type 3 Dearing (ReoT3D), a wild type oncolytic virus (OV) from the Reoviridae family, kills KRAS mutant cancer cells. However, the use of OVs has faced with some limitations such as immune responses, and delivery of OVs to the tumor sites in systemic therapy. To solve this, and als...