Dose‐dependent effects of esketamine on brain activity in awake mice: A BOLD phMRI study

• Main Authors: Kyrsten Kawazoe (Author), Ryan McGlynn (Author), Wilder Felix (Author), Raquel Sevilla (Author), Siyang Liao (Author), Praveen Kulkarni (Author), Craig F. Ferris (Author)
• Format: Book
• Published: Wiley, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Pharmacological magnetic resonance imaging (phMRI) is a noninvasive method used to evaluate neural circuitry involved in the behavioral effects of drugs like ketamine, independent of their specific biochemical mechanism. The study was designed to evaluate the immediate effect of esketamine,...