Physical exercise elicits UPRmt in the skeletal muscle: The role of c-Jun N-terminal kinase

• Main Authors: Rodrigo Stellzer Gaspar (Author), Carlos Kiyoshi Katashima (Author), Barbara Moreira Crisol (Author), Fernanda Silva Carneiro (Author), Igor Sampaio (Author), Leonardo dos Reis Silveira (Author), Adelino Sanchez Ramos da Silva (Author), Dennys Esper Cintra (Author), José Rodrigo Pauli (Author), Eduardo Rochete Ropelle (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The mitochondrial unfolded protein response (UPRmt) is an adaptive cellular response to stress to ensure mitochondrial proteostasis and function. Here we explore the capacity of physical exercise to induce UPRmt in the skeletal muscle. Methods: Therefore, we combined mouse models of exerc...