Preliminary Assessment of Intramuscular Depot of Lipid-Based Decoquinate Formulation for Long-Term Chemoprophylaxis of Malaria

• Κύριοι συγγραφείς: Yinzhou Fan (Συγγραφέας), Li Qin (Συγγραφέας), Zhenping Huang (Συγγραφέας), Shuanghong Liang (Συγγραφέας), Xiaoyi Huang (Συγγραφέας), Sumei Zeng (Συγγραφέας), Yucheng Liu (Συγγραφέας), Hongxing Wang (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2022-12-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Sustained-release formulations of decoquinate were evaluated for the long-term prophylaxis of malaria. In the initial experiment, mice were protected from liver-stage <i>Plasmodium</i> infection by intramuscular administration of a lipids-based formulation at a dose of decoquinate 200 mg...