Downregulation of α7 nicotinic acetylcholine receptors in peripheral blood monocytes is associated with enhanced inflammation in preeclampsia

• मुख्य लेखकों: Hongmei Xu (लेखक), Qingyang Shi (लेखक), Yanxiang Mo (लेखक), Linlin Wu (लेखक), Jishuang Gu (लेखक), Ying Xu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2019-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Preeclampsia is associated with chronic inflammation. The cholinergic anti-inflammatory pathway regulates systemic inflammation through activating α7 nicotinic acetylcholine receptors (α7nAChR) expressed in monocytes/macrophages. This study aimed to investigate the role of α7nACh...