Downregulation of α7 nicotinic acetylcholine receptors in peripheral blood monocytes is associated with enhanced inflammation in preeclampsia

• প্রধান লেখক: Hongmei Xu (লেখক), Qingyang Shi (লেখক), Yanxiang Mo (লেখক), Linlin Wu (লেখক), Jishuang Gu (লেখক), Ying Xu (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2019-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background Preeclampsia is associated with chronic inflammation. The cholinergic anti-inflammatory pathway regulates systemic inflammation through activating α7 nicotinic acetylcholine receptors (α7nAChR) expressed in monocytes/macrophages. This study aimed to investigate the role of α7nACh...