Identification of PARP12 Inhibitors By Virtual Screening and Molecular Dynamics Simulations

Poly [adenosine diphosphate (ADP)-ribose] polymerases (PARPs) are members of a family of 17 enzymes that performs several fundamental cellular processes. Aberrant activity (mutation) in PARP12 has been linked to various diseases including inflammation, cardiovascular disease, and cancer. Herein, a l...

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Main Authors: Tahani M. Almeleebia (Author), Shahzaib Ahamad (Author), Irfan Ahmad (Author), Ahmad Alshehri (Author), Ali G. Alkhathami (Author), Mohammad Y. Alshahrani (Author), Mohammed A. Asiri (Author), Amir Saeed (Author), Jamshaid Ahmad Siddiqui (Author), Dharmendra K. Yadav (Author), Mohd Saeed (Author)
Format: Book
Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
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