Identification of PARP12 Inhibitors By Virtual Screening and Molecular Dynamics Simulations

• 主要な著者: Tahani M. Almeleebia (著者), Shahzaib Ahamad (著者), Irfan Ahmad (著者), Ahmad Alshehri (著者), Ali G. Alkhathami (著者), Mohammad Y. Alshahrani (著者), Mohammed A. Asiri (著者), Amir Saeed (著者), Jamshaid Ahmad Siddiqui (著者), Dharmendra K. Yadav (著者), Mohd Saeed (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Poly [adenosine diphosphate (ADP)-ribose] polymerases (PARPs) are members of a family of 17 enzymes that performs several fundamental cellular processes. Aberrant activity (mutation) in PARP12 has been linked to various diseases including inflammation, cardiovascular disease, and cancer. Herein, a l...