MTSET modification of D4S6 cysteines stabilize the fast inactivated state of Nav1.5 sodium channels
The transmembrane S6 segments of Na+ sodium channels form the cytoplasmic entrance of the channel and line the internal aspects of the aqueous pore. This region of the channel has been implicated in Na+ channel permeation, gating and pharmacology. In this study we utilized cysteine substitutions and...
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Frontiers Media S.A.,
2015-06-01T00:00:00Z.
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