Impact of Gastric H+/K+-ATPase rs2733743 on the Intragastric pH-Values of Dexlansoprazole Injection in Chinese Subjects

• Main Authors: Lu-Ning Sun (Author), Yang Cao (Author), Yue-Qi Li (Author), Yun-Qian Fang (Author), Hong-Wen Zhang (Author), Mei-Feng Wang (Author), Li-Jun Xie (Author), Juan Chen (Author), Zhi-Cheng Yang (Author), Ming-Liang Bian (Author), Hao Li (Author), Pei-Pei Zhang (Author), Ji-Fu Wei (Author), Ling Meng (Author), Xue-Hui Zhang (Author), Ping Zhao (Author), Yong-Qing Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Not all patients with acid-related disorders receiving proton pump inhibitor (PP) treatment get adequate gastric pH control. The genetic variation of receptors, metabolic enzymes, and transporters are known to cause failures of therapies. We have conducted a study to evaluate the influen...