Therapeutic Effect of Extracellular Vesicles Derived from HIF Prolyl Hydroxylase Domain Enzyme Inhibitor-Treated Cells on Renal Ischemia/Reperfusion Injury

• Main Authors: Zhao-Ying Ding (Author), Tao-Tao Tang (Author), Zuo-Lin Li (Author), Jing-Yuan Cao (Author), Lin-Li Lv (Author), Yi Wen (Author), Bin Wang (Author), Bi-Cheng Liu (Author)
• Format: Book
• Published: Karger Publishers, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Acute kidney injury (AKI) is a major public health problem worldwide. However, there is no definitive therapies to treat established AKI. In this study, we used FG-4592 to induce hypoxia inducible factor (HIF) expression in cells and then explored whether the extracellular vesicles (EV...