Case Report: Comparison of Plasma Metagenomics to Bacterial PCR in a Case of Prosthetic Valve Endocarditis

• Main Authors: Joshua A. Lieberman (Author), Caitlin Naureckas Li (Author), Gabriella S. Lamb (Author), David A. Kane (Author), Mary K. Stewart (Author), Ruslan A. Mamedov (Author), Brad T. Cookson (Author), Stephen J. Salipante (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Molecular assays for infectious diseases have emerged as important clinical decision-making tools. Unbiased, metagenomic next-generation sequencing is a novel approach holding promise to detect pathogens missed by conventional modalities and to deconvolute admixed nucleic acid sequences from polymic...