Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase.

• Main Authors: Alex P McLatchie (Author), Hollie Burrell-Saward (Author), Elmarie Myburgh (Author), Michael D Lewis (Author), Theresa H Ward (Author), Jeremy C Mottram (Author), Simon L Croft (Author), John M Kelly (Author), Martin C Taylor (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human African trypanosomiasis is caused by infection with parasites of the Trypanosoma brucei species complex, and threatens over 70 million people in sub-Saharan Africa. Development of new drugs is hampered by the limitations of current rodent models, particularly for stage II infections, which occ...