Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages

• Main Authors: Tao Wang (Author), Zhuo Lu (Author), Xin-Hui Qu (Author), Zi-Ying Xiong (Author), Ya-Ting Wu (Author), Yong Luo (Author), Zi-Yu Zhang (Author), Xiao-Jian Han (Author), Cai-Feng Xie (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute liver failure (ALF) is an unfavorable condition characterized by the rapid loss of liver function and high mortality. Chrysophanol-8-O-glucoside (CPOG) is an anthraquinone derivative isolated from rhubarb. This study aims to evaluate the protective effect of CPOG on lipopolysaccharide (LPS)/D-...