An Overview of the Protein Binding of Cephalosporins in Human Body Fluids: A Systematic Review

• Main Authors: C. Jongmans (Author), A. E. Muller (Author), P. Van Den Broek (Author), B. De Melo Cruz De Almeida (Author), C. Van Den Berg (Author), J. Van Oldenrijk (Author), P. K. Bos (Author), B. C. P. Koch (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Protein binding can diminish the pharmacological effect of beta-lactam antibiotics. Only the free fraction has an antibacterial effect. The aim of this systematic literature review was to give an overview of the current knowledge of protein binding of cephalosporins in human body fluid...