Exploration of broadly neutralizing antibody fragments produced in bacteria for the control of HIV

• Main Authors: Sarah B. Lloyd (Author), Keith P. Niven (Author), Ben R. Kiefel (Author), David C. Montefiori (Author), Arnold Reynaldi (Author), Miles P. Davenport (Author), Stephen J. Kent (Author), Wendy R. Winnall (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

While broadly neutralizing antibodies (bnAbs) are a promising preventative and therapeutic tool for HIV infection, production is difficult and expensive. Production of antibody-like fragments in bacterial cytoplasm provides a cheaper alternative. This work explored the transplantation of the complem...