Structural modification of resveratrol analogue exhibits anticancer activity against lung cancer stem cells via suppression of Akt signaling pathway

• Main Authors: Sunisa Thongsom (Author), Satapat Racha (Author), Korrakod Petsri (Author), Zin Zin Ei (Author), Kittichate Visuttijai (Author), Sohsuke Moriue (Author), Masashi Yokoya (Author), Pithi Chanvorachote (Author)
• פורמט: ספר
• יצא לאור: BMC, 2023-06-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Background Compound with cancer stem cell (CSC)-suppressing activity is promising for the improvement of lung cancer clinical outcomes. Toward this goal, we discovered the CSC-targeting activity of resveratrol (RES) analog moscatilin (MOS). With slight structural modification from RES, MOS...