Stress increases blood beta‐hydroxybutyrate levels and prefrontal cortex NLRP3 activity jointly in a rodent model

• Main Authors: Tsuyoshi Nishiguchi (Author), Masaaki Iwata (Author), Naofumi Kajitani (Author), Akihiko Miura (Author), Ryoichi Matsuo (Author), Shumei Murakami (Author), Yumeto Nakada (Author), Shenghong Pu (Author), Yuki Shimizu (Author), Tatsuya Tsubakino (Author), Takehiko Yamanashi (Author), Gen Shinozaki (Author), Jun Tsubota (Author), Yukihiko Shirayama (Author), Ken Watanabe (Author), Koichi Kaneko (Author)
• Format: Book
• Published: Wiley, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aim This study aimed to assess the response of endogenous beta‐hydroxybutyrate to psychological stress, and its association with nucleotide‐binding domain, leucine‐rich repeat, pyrin domain‐containing 3 (NLRP3) inflammasome, and stress‐induced behavior. Methods Male C57BL/6J mice were subje...