Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase

• Main Authors: Quanjie Li (Author), Dongrong Yi (Author), Xiaobo Lei (Author), Jianyuan Zhao (Author), Yongxin Zhang (Author), Xiangling Cui (Author), Xia Xiao (Author), Tao Jiao (Author), Xiaojing Dong (Author), Xuesen Zhao (Author), Hui Zeng (Author), Chen Liang (Author), Lili Ren (Author), Fei Guo (Author), Xiaoyu Li (Author), Jianwei Wang (Author), Shan Cen (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become one major threat to human population health. The RNA-dependent RNA polymerase (RdRp) presents an ideal target of antivirals, whereas nucleoside analogs inhibitor is hindered by the proofreading activity of coronavirus. Herein, w...