Microencapsulation of <i>Salmonella</i>-Specific Bacteriophage Felix O1 Using Spray-Drying in a pH-Responsive Formulation and Direct Compression Tableting of Powders into a Solid Oral Dosage Form

• Autores principales: Gurinder K. Vinner (Autor), Zahra Rezaie-Yazdi (Autor), Miika Leppanen (Autor), Andrew G.F. Stapley (Autor), Mark C. Leaper (Autor), Danish J. Malik (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2019-03-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The treatment of enteric bacterial infections using oral bacteriophage therapy can be challenging since the harsh acidic stomach environment renders phages inactive during transit through the gastrointestinal tract. Solid oral dosage forms allowing site-specific gastrointestinal delivery of high dos...