Berberine Mitigates Sepsis-Associated Acute Kidney Injury in Aged Rats by Preserving Mitochondrial Integrity and Inhibiting TLR4/NF-κB and NLRP3 Inflammasome Activations

• Váldodahkkit: Ruedeemars Yubolphan (Dahkki), Anongporn Kobroob (Dahkki), Apisek Kongkaew (Dahkki), Natthakarn Chiranthanut (Dahkki), Natthanicha Jinadang (Dahkki), Orawan Wongmekiat (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2024-11-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Sepsis-associated acute kidney injury (SA-AKI) presents a severe challenge in the elderly due to increasing incidence, high mortality, and the lack of specific effective treatments. Exploring novel and secure preventive and/or therapeutic approaches is critical and urgent. Berberine (BBR), an isoqui...