Berberine Mitigates Sepsis-Associated Acute Kidney Injury in Aged Rats by Preserving Mitochondrial Integrity and Inhibiting TLR4/NF-κB and NLRP3 Inflammasome Activations

• Principais autores: Ruedeemars Yubolphan (Autor), Anongporn Kobroob (Autor), Apisek Kongkaew (Autor), Natthakarn Chiranthanut (Autor), Natthanicha Jinadang (Autor), Orawan Wongmekiat (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2024-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Sepsis-associated acute kidney injury (SA-AKI) presents a severe challenge in the elderly due to increasing incidence, high mortality, and the lack of specific effective treatments. Exploring novel and secure preventive and/or therapeutic approaches is critical and urgent. Berberine (BBR), an isoqui...