Berberine Mitigates Sepsis-Associated Acute Kidney Injury in Aged Rats by Preserving Mitochondrial Integrity and Inhibiting TLR4/NF-κB and NLRP3 Inflammasome Activations

• Päätekijät: Ruedeemars Yubolphan (Tekijä), Anongporn Kobroob (Tekijä), Apisek Kongkaew (Tekijä), Natthakarn Chiranthanut (Tekijä), Natthanicha Jinadang (Tekijä), Orawan Wongmekiat (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2024-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Sepsis-associated acute kidney injury (SA-AKI) presents a severe challenge in the elderly due to increasing incidence, high mortality, and the lack of specific effective treatments. Exploring novel and secure preventive and/or therapeutic approaches is critical and urgent. Berberine (BBR), an isoqui...